In a study entitled “Pharmacotherapeutic considerations for use of cannabinoids to relieve pain in patients with malignant diseases” researchers determined that CBD may help reduce chronic pain by impacting endocannabinoid receptor activity, reducing inflammation and interacting with neurotransmitters.
Animal studies, such as “Cannabidiol Is a Potential Therapeutic for the Affective-Motivational Dimension of Incision Pain in Rats” have shown that CBD reduced pain response to surgical incision and reduced sciatic nerve pain and inflammation.
In a study on depression and anxiety entitled “Cannabidiol Reduces the Anxiety Induced by Simulated Public Speaking in Treatment-Naïve Social Phobia Patients” researchers determined that a group of social anxiety sufferers who received CBD had significantly less anxiety, cognitive impairment and discomfort before a speech performance than those receiving a placebo.
“Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain” showed that a THC:CBD extract is efficacious for relief of pain in patients with advanced cancer pain not fully relieved by strong opioids.
“Delayed nausea and vomiting continue to reduce patients' quality of life after highly and moderately emetogenic chemotherapy despite antiemetic treatment” showed that CBD may help reduce chemotherapy-induced nausea and vomiting.
“Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes” showed that CBD has potential as a promising therapeutic agent for the treatment of acne.
“Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trial” showed that cannabidiol might reduce seizure frequency and might have an adequate safety profile in children and young adults with highly treatment-resistant epilepsy.
“A single dose of cannabidiol reduces blood pressure in healthy volunteers in a randomized crossover study” found that CBD reduced resting blood pressure compared to a placebo.
The animal study “The Antitumor Activity of Plant-Derived Non-Psychoactive Cannabinoids” found that CBD may stop brain, prostate, breast, colon and lung cancers from spreading.